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    Immediate effects of soft tissue mobilization and percussive massage on balance in young adults with pes planus: A single blind, randomized controlled pilot study
    (Churchill Livingstone, 2024) Kethüdaoğlu, M.O.; Özdemir, A.E.; Kaya Sağlam, Ö.; Çağlar, E.; Meran Çağlar, M.; Demir, G.; Duymaz, T.
    Background: Presence of pes planus is known to effect balance. In this study, it was aimed to examine the immediate effects of IASTM and PMT on static and dynamic balance in young adults with pes planus. Method: The navicular drop test was used to diagnose pes planus. 51 individuals were included in the study and divided into three groups [IASTM (n:15), percussive massage (n:18) and control (n:18) groups] by simple randomization. Flamingo and Y Balance test was assessed before and immediately after intervention. Repeated Measures ANOVA test was used for the intergroup comparison, and the One-Way ANOVA test was used for the intragroup comparison, also post-hoc test with Tukey correction was performed. Results: There was no significant difference in static balance between the three groups (p > 0.05). There was a significant difference in dynamic balance between groups (p < 0.05). Only IASTM group had significant differences at before and after intervention of all directions except for posterolateral direction of Y Balance Test (p < 0.05). Conclusion: IASTM applied to the plantar fascia of individuals with pes planus have immediate effects on dynamic balance when compared to no intervention and percussive massage even within a small sample size. © 2024 Elsevier Ltd
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    Intra- and Extra-cellular Thiol-Disulfide Homeostasis in Blood of Patients with Alcohol Use Disorder
    (Pleiades Publishing Inc, 2021) Sogut, I; Senat, A.; Kabadayi-Sahin, E.; Duymaz, T.; Erel, O.
    Alcohol use disorder (AUD) is the loss of a person's quality of life due to increased alcohol consumption and the failure of alcohol consumption control. In this study, the intra- and extracellular thiol-disulfide levels in people with AUD were compared with age-matched healthy controls. Forty male patients diagnosed with AUD and thirty healthy male individuals were included in the study. In addition to psychiatric and sociodemographic tests routine biochemical evaluations have been performed. The alcohol group had significantly higher Michigan Alcohol Screening Test (MAST), Beck Depression Inventory (BDI), and Beck Anxiety Inventory (BAI) scores compared to the control group. While there was a decrease in the intracellular GSH and extracellular native thiol levels in the blood of the alcohol group, GSSG and disulfide levels were increased, respectively. Subsequently, while there was an increase in the intracellular GSSG/GSH content levels in the alcohol group compared to the control group, the ratios of GSH/GSH+GSSG were decreased. These changes, indicative of oxidative stress, were observed both in blood serum and erythrocytes. Also, there was an increase in alanine aminotransferase (ALT), aspartate aminotransferase (AST), gamma-glutamyltransferase (GGT) mean corpuscular volume (MCV), C-reactive protein (CRP) levels in the alcohol group in routine biochemical tests, while total protein, folic acid, ferritin and hemoglobin (HGB) levels were decreased. Our results suggest that increased intra- and extracellular GSSG/GSH % (disulfide/native thiol %) may serve as an indicator of developing oxidative stress in individuals with AUD.
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    Study on the relationship between low back pain and emotional state, sleep and quality of life in postmenopausal women
    (Ios Press, 2020) Duymaz, T.; Yagci, N.; Gayef, A.; Telatar, B.
    OBJECTIVE: The aim of this study was to investigate the incidence of low back pain in the postmenopausal period and the relationship between low back pain and emotional state, sleep and quality of life. METHODS: This cross-sectional study was conducted with 368 postmenopausal women between 40 and 65 years old. The frequency and severity of low back pain were recorded for all participants, as well as depressive symptoms and anxiety, quality of life and sleep quality. RESULTS: 90.2% of the participants reported low back pain. As low back pain severity increased, it was found that depression, anxiety levels, NHP and PSQI total scores increased as well (p = 0.0001). Significant positive correlations were found between pain intensity and outcome measures, except for sleep duration and habitual sleep efficiency (p < 0.01). CONCLUSION: A great majority of women experience postmenopausal low back pain, which causes significant problems that negatively affect their quality of life, emotional state and sleep quality.