Cost-effective, microstrip antenna driven ring resonator microwave biosensor for biospecific detection of glucose

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dc.authorscopusid56182670300
dc.authorscopusid56766135200
dc.authorscopusid58675004100
dc.authorscopusid14054860700
dc.authorscopusid16240112200
dc.authorscopusid13105641900
dc.contributor.authorCamli, B.
dc.contributor.authorKusakci, E.
dc.contributor.authorLafci, B.
dc.contributor.authorSalman, S.
dc.contributor.authorTorun, H.
dc.contributor.authorYalcinkaya, A.D.
dc.date.accessioned2024-07-18T20:17:10Z
dc.date.available2024-07-18T20:17:10Z
dc.date.issued2017
dc.description.abstractWe present a biosensor based on electromagnetic ring resonator for label-free detection of glucose. The sensing mechanism is based on the principle that the resonant frequencies of such structures depend on the structure geometry and the physical properties of the medium they are in, such as electrical permittivity. The sensor in this paper uses a split-ring resonator fabricated on a flame retardant four substrate via simple printed circuit board fabrication techniques. Glucose oxidase enzyme was incorporated in order to provide biospecificity for glucose. Conductive polymer poly(3,4-ethylenedioxythiophene)poly(styrenesulfonate), also known as PEDOT:PSS, was used for the immobilization of the enzyme on sensor surface. The redshift of the resonant frequency of the sensor in response to DI water, glucose, and NaCl solutions are shown to be in agreement with simulation results and theoretical expectations. In the presence of the enzyme, the sensor loaded with a glucose solution was observed to experience a resonant frequency shift of 17.5 MHz in 15 min, whereas other reagents such as fructose, sucrose, and NaCl did not respond significantly, confirming the biospecificity. The sensor was measured to have a sensitivity of 0.107 MHz/mgml-1. © 1995-2012 IEEE.en_US
dc.description.sponsorshipTürkiye Bilimler Akademisi; 112E250; Türkiye Bilimsel ve Teknolojik Araştirma Kurumu, TÜBITAK; British Association for Psychopharmacology, BAP: 16A02TUG4en_US
dc.description.sponsorshipThis work was supported by the Turkish Academy of Sciences (TUBA), the Scientific and Technological Research Council of Turkey (TUBITAK) under Project 112E250, and the Department of Scientific Research of Bogazici University (BAP) under Project 16A02TUG4en_US
dc.identifier.doi10.1109/JSTQE.2017.2659226
dc.identifier.endpage409en_US
dc.identifier.issn1077-260X
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-85017620828en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage404en_US
dc.identifier.urihttps://doi.org/10.1109/JSTQE.2017.2659226
dc.identifier.urihttps://hdl.handle.net/11411/6426
dc.identifier.volume23en_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherInstitute of Electrical and Electronics Engineers Inc.en_US
dc.relation.ispartofIEEE Journal of Selected Topics in Quantum Electronicsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBiosensorsen_US
dc.subjectGlucoseen_US
dc.subjectGoxen_US
dc.subjectMetamaterialsen_US
dc.subjectSplit Ring Resonatorsen_US
dc.subjectBiosensorsen_US
dc.subjectConducting Polymersen_US
dc.subjectCost Effectivenessen_US
dc.subjectEnzyme İmmobilizationen_US
dc.subjectGlucoseen_US
dc.subjectGlucose Sensorsen_US
dc.subjectMetamaterialsen_US
dc.subjectMicrostrip Antennasen_US
dc.subjectMicrowave Resonatorsen_US
dc.subjectNatural Frequenciesen_US
dc.subjectOptical Resonatorsen_US
dc.subjectPrinted Circuit Boardsen_US
dc.subjectRing Gagesen_US
dc.subjectSodium Chlorideen_US
dc.subjectSubstratesen_US
dc.subjectElectrical Permittivityen_US
dc.subjectFabrication Techniqueen_US
dc.subjectLabel-Free Detectionen_US
dc.subjectPoly(Styrene Sulfonate)en_US
dc.subjectPoly-3 ,4-Ethylenedioxythiopheneen_US
dc.subjectResonant Frequency Shiften_US
dc.subjectSplit Ring Resonatoren_US
dc.subjectStructure Geometryen_US
dc.subjectGlucose Oxidaseen_US
dc.titleCost-effective, microstrip antenna driven ring resonator microwave biosensor for biospecific detection of glucoseen_US
dc.typeArticleen_US

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