A dosimetric comparison for SBRT plans of localized prostate cancer between Cyberknife and Varian Truebeam STX device

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dc.authoridSenisik, Ahmet Murat/0000-0002-7781-3355
dc.authorwosidSenisik, Ahmet Murat/I-8635-2018
dc.contributor.authorSenisik, Ahmet Murat
dc.contributor.authorOkutan, Murat
dc.contributor.authorCakir, Aydin
dc.contributor.authorCelik, Ayca Iribas
dc.contributor.authorSaglam, Esra Kaytan
dc.contributor.authorCevikbas, Gorkem
dc.contributor.authorDemir, Bayram
dc.date.accessioned2024-07-18T20:42:29Z
dc.date.available2024-07-18T20:42:29Z
dc.date.issued2023
dc.departmentİstanbul Bilgi Üniversitesien_US
dc.description.abstractAs the Stereotactic Body Radiotherapy (SBRT) approach began to increase in treating patients with localized prostate cancer, it became necessary to investigate which methods used in practice were better. The aim of this study is to perform a dosimetric comparison of the advantages and disadvantages of SBRT treatments for localized prostate cancer delivered by CyberKnife (CK) and Varian Truebeam STX (FF and FFF). Seventeen in-termediate and high-risk patients with localized prostate cancer were included in the study. SBRT plans for the CK system and Varian Truebeam STX systems with and without Flattening Filters (Tru-FF and Tru-FFF) were prepared for each patient. Plans prepared for each patient were planned at a fraction dose of 6.7 Gy at 6 MV energy and a target dose of 33.5 Gy in 5 fractions. For all plans, cumulative dose-volume histograms (DVHs) were generated for target volumes and organs at risk (OAR). The maximum doses of PTV (41 Gy) in CK plans are higher than the maximum doses (35 Gy) in VMAT plans prepared with Tru-FF or Tru-FFF beams. The mean dose of the rectal wall (10.06 ?? 2.40Gy for CK) is still relatively low compared to other plans (13.46 ?? 2.16 Gy for Tru-FF and 13.61 ?? 2.32 Gy for Tru-FFF). The bladder wall (14 Gy for CK, 26 Gy for Tru-FF and Tru-FFF) and femoral head (6.8 Gy for CK, 9 Gy for Tru-FF and 9.4 Gy Tru-FFF) doses were also lower for CK plans. The CK plans provide better tumour control due to low doses in critical organs and high target doses than the Tru-FF or Tru-FFF plans. It was observed that CK and VMAT plans for SBRT with 6 MV photon beams provided acceptable results in term of treatment planning criteria such as Conformity Index and Homogeneity Index. It is recom-mended to use a target tracking system to provide an accurate and reliable SBRT treatment with VMAT and CK techniques.en_US
dc.identifier.doi10.1016/j.apradiso.2022.110617
dc.identifier.issn0969-8043
dc.identifier.issn1872-9800
dc.identifier.pmid36538872en_US
dc.identifier.scopus2-s2.0-85144347240en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.urihttps://doi.org/10.1016/j.apradiso.2022.110617
dc.identifier.urihttps://hdl.handle.net/11411/7291
dc.identifier.volume192en_US
dc.identifier.wosWOS:000904000100002en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherPergamon-Elsevier Science Ltden_US
dc.relation.ispartofApplied Radiation and Isotopesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectLocalized Prostate Canceren_US
dc.subjectVolumetric Modulated Arc Therapy (Vmat)en_US
dc.subjectStereotactic Body Radiotherapy (Sbrt)en_US
dc.subjectCyberknife (Ck)en_US
dc.subjectModulated Arc Therapyen_US
dc.subjectFlattening Filter Ffen_US
dc.subjectRadiotherapyen_US
dc.titleA dosimetric comparison for SBRT plans of localized prostate cancer between Cyberknife and Varian Truebeam STX deviceen_US
dc.typeArticleen_US

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