Synthesis of molecularly imprinted polymers for specific recognition of ellagic acid

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dc.authoridCakir Hatir, Pinar/0000-0002-3806-7118|Gulen, Hatice/0000-0001-7586-3108
dc.authorwosidCakir Hatir, Pinar/S-8707-2019
dc.authorwosidGulen, Hatice/AFW-5375-2022
dc.contributor.authorYucel, Necla
dc.contributor.authorGulen, Hatice
dc.contributor.authorHatir, Pinar Cakir
dc.date.accessioned2024-07-18T20:52:16Z
dc.date.available2024-07-18T20:52:16Z
dc.date.issued2019
dc.departmentİstanbul Bilgi Üniversitesien_US
dc.descriptionInternational Scientific Meeting on Electrical-Electronics and Biomedical Engineering and Computer Science (EBBT) -- APR 24-26, 2019 -- Istanbul Arel Univ, Kemal Gozukara Campus, Istanbul, TURKEYen_US
dc.description.abstractMolecular imprinting technique is based on the fact that functional monomers are formed a complex around the template molecule by covalent or non-covalent interactions, and then these interactions are made stable by using cross-linker. By the removal of the template molecule after the synthesis, the template molecule-specific complementary binding sites are formed in the polymeric network. The ellagic acid molecule, which is found in the pomegranate fruit, is known to have anti-inflammatory, antiallergic, anti-cancer and antimicrobial properties. In this study, it is aimed to synthesize ellagic acid imprinted polymer (MIP) for isolation of ellagic acid from pomegranate fruit. 4-vinylpyridine was used as functional monomer, ethylene glycol dimethacrylate as crosslinker, and Tetramethylethylenediamine (TEMED)/Potassium persulfate (KPS) system as initiator. Molecularly imprinted polymers were synthesized by thermal polymerization. The characterization of the synthesized polymers was done by Fourier-transform infrared spectroscopy (FTIR). The ellagic acid recognition properties of MIP and nonimprinted polymers (NIPs) were tested, dissociation constants were calculated as 7.0 mu M for MIP and 9.5 mu M with lower affinity for NIP. In the light of the findings, it was concluded that MIP can recognize ellagic acid better than NIP.en_US
dc.description.sponsorshipIEEE Turkey Sect,IEEE EMB,Erasmus+,Europassen_US
dc.identifier.isbn978-1-7281-1013-4
dc.identifier.scopus2-s2.0-85068581905en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.urihttps://hdl.handle.net/11411/8611
dc.identifier.wosWOS:000491430200011en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isotren_US
dc.publisherIEEEen_US
dc.relation.ispartof2019 Scientific Meeting on Electrical-Electronics & Biomedical Engineering and Computer Science (Ebbt)en_US
dc.relation.publicationcategoryKonferans Öğesi - Uluslararası - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectMolecularly İmprinted Polymersen_US
dc.subjectEllagic Aciden_US
dc.subjectSpesific Recognitionen_US
dc.subjectPomegranate Extracten_US
dc.subjectAntioxidanten_US
dc.subjectBindingen_US
dc.titleSynthesis of molecularly imprinted polymers for specific recognition of ellagic aciden_US
dc.typeConference Objecten_US

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