Comparison Between the Effects of Preoperative (Preemptive) and Intraoperative use of Tramadol on Post-Operative Pain

dc.WoS.categoriesMedicine, General & Internalen_US
dc.contributor.authorGül, Yaşar Gökhan
dc.contributor.authorŞener, Tufan
dc.contributor.authorKöprülü, Ali Şefik
dc.contributor.authorHaspolat, Ali
dc.contributor.authorNeymen, Bülent
dc.date.accessioned2020-12-23T07:40:11Z
dc.date.available2020-12-23T07:40:11Z
dc.date.issued2015-09
dc.description.abstractAim: The aim of this study was to investigate the efficiency of tramadol treatment in prevention of postoperative pain in two different groups in which tramadol applied before skin incision (group 1/preemptive), and intraoperatively (group 2/preventive) at the same dose. Methods: The study was designed as a randomized prospective study. The patients in group 1 (n=25) received 1.5 mg/kg tramadol IV 15 minutes before induction of anesthesia. The patients in group 2 (n=25) received the same dose of tramadol after the incision. Postoperative pain was assessed with 10 cm visual analogue scale (VAS) after extubation, before the first analgesic request and at the 6th, 12th, 18th and 24th hours, postoperatively. Paracetamole (15 mg/kg) and, if it was not sufficient, pethidine (1 mg/kg) were used for postoperative analgesia. Total doses of analgesics and side effects were recorded. Results: This study showed no significant differences in pain scores and total doses of analgesics except for time to first analgesic requirement [(t(analgezia)) 24.21 +/- 8.2 min. in group 1 and 42.18 +/- 9.8 min. in group 2]. Conclusion: In this study, any difference between preemptive and preventive properties of iv tramadol could not be demonstrated. Applying route of tramadol and the possibility that anesthetic drugs can suppress central sensitization are thought to be reasons.en_US
dc.fullTextLevelFull Texten_US
dc.identifier.doi10.4274/haseki.2389
dc.identifier.issn2147-2688
dc.identifier.issn1302-0072
dc.identifier.urihttps://hdl.handle.net/11411/2964
dc.identifier.urihttps://doi.org/10.4274/haseki.2389
dc.identifier.wosWOS:000216755500009en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.issue3en_US
dc.language.isotren_US
dc.nationalInternationalen_US
dc.numberofauthors5en_US
dc.pages220-224en_US
dc.publisherGalenos Yayıncılıken_US
dc.relation.ispartofHASEKI TIP BULTENI-MEDICAL BULLETIN OF HASEKIen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectTramadolen_US
dc.subjectpreemptive analgesiaen_US
dc.subjectpostoperative painen_US
dc.titleComparison Between the Effects of Preoperative (Preemptive) and Intraoperative use of Tramadol on Post-Operative Pain
dc.typeArticle
dc.volume53en_US

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