Prognostic Value of Right Ventricular Cardiac Power Output at Rest in Patients with Advanced Heart Failure

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dc.authoridYildiz, Omer/0000-0002-3632-3405
dc.contributor.authorYildiz, Omer
dc.contributor.authorYenigun, Cemal Deniz
dc.date.accessioned2024-07-18T20:50:48Z
dc.date.available2024-07-18T20:50:48Z
dc.date.issued2021
dc.departmentİstanbul Bilgi Üniversitesien_US
dc.description.abstractBackground: There is supporting evidence that normal right heart function is crucial for the maintenance of normal overall hemodynamics. The heart can be described as a hydraulic pump, and cardiac power reflects the hydraulic function of the heart. The present analysis aimed to evaluate the prognostic value of right ventricular cardiac power output (RV-CPO) at rest in patients with advanced heart failure (HF). Methods: Between September 2010 and July 2013, 172 patients with advanced HF referred to our hospital were included in this study. Performing right-sided and left-sided heart catheterization simultaneously for each patient at baseline, we evaluated the hemodynamics with longitudinal follow-up of adverse outcomes such as cardiac mortality, ventricular assist device placement, and cardiac transplant (HTx). Results: The threshold RV-CPO at rest value was 0.15 Watts. Increased RV-CPO (> 0.15 Watts) was correlated with an increase in adverse outcomes. Over 52 months, we observed 50 cardiac deaths, 10 HTx, and 12 ventricular assist device placements. The prognostic value of RV-CPO remained significant after adjustment for age, gender, ejection fraction, cardiac output, mean arterial pressure, valvular heart disease, diabetes, body surface area and mineralocorticoid receptor antagonist medication dummy (hazard ratio 0.052, 95% confidence interval 0.006 to 0.406, p = 0.005). Conclusions: Higher RV-CPO at rest was an independent predictor of adverse outcomes. Therefore, RV-CPO could be integrated into the clinical evaluation used for individual risk stratification of patients with advanced HF in order to consider earlier HTx listing and/or earlier consideration for mechanical circulatory support device therapy.en_US
dc.identifier.doi10.6515/ACS.202107_37(4).20210123A
dc.identifier.endpage411en_US
dc.identifier.issn1011-6842
dc.identifier.issue4en_US
dc.identifier.pmid34257490en_US
dc.identifier.scopus2-s2.0-85112465733en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage404en_US
dc.identifier.urihttps://doi.org/10.6515/ACS.202107_37(4).20210123A
dc.identifier.urihttps://hdl.handle.net/11411/8243
dc.identifier.volume37en_US
dc.identifier.wosWOS:000674682900007en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTaiwan Soc Cardiologyen_US
dc.relation.ispartofActa Cardiologica Sinicaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectHeart Failureen_US
dc.subjectMortalityen_US
dc.subjectPrognosisen_US
dc.subjectRight Ventricular Cardiac Power Outputen_US
dc.subjectPulmonary-Hypertensionen_US
dc.subjectEjection Fractionen_US
dc.titlePrognostic Value of Right Ventricular Cardiac Power Output at Rest in Patients with Advanced Heart Failure
dc.typeArticle

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