Mucositis-Induced Pain due to Barrier Dysfunction may have a Direct Effect on Nutritional Status and Quality of Life in Head and Neck Cancer Patients Receiving Radiotherapy

Basit Öğe Kaydı
dc.WoS.categoriesOncologyen_US
dc.authorid0000-0003-3897-1446en_US
dc.contributor.authorAtasoy, Beste M.
dc.contributor.authorKayhan, Kıvanç Bektaş
dc.contributor.authorDemirel, Birsen
dc.contributor.authorAkdeniz, Esra
dc.date.accessioned2020-12-22T09:27:59Z
dc.date.available2020-12-22T09:27:59Z
dc.date.issued2020
dc.description.abstractOBJECTIVE To maintain the barrier function against mucositis-induced pain and to improve the nutritional status and quality of life in head and neck cancer patients during radiotherapy. METHODS All patients (n=30) used oral gel to reduce mucositis-induced pain. Patients were examined weekly for the severity of mucositis, pain and nutritional status. The quality of life parameters was measured at the beginning and at the end of treatment. There was no restriction for pain killers against mucositis. RESULTS The only significant factor affecting the severity and frequency of mucositis was the cumulative radiation dose (p<0.001). Despite the regular use of oral gel, weight loss was observed in 65% of the patients. There was no difference concerning the severity of mucositis, cumulative radiation doses, or mean dose of oral mucosa between patients with no risk or at risk, according to SGA. However, self-assessment pain scores were significantly better in the well-nourished group (p=0.05 vs. 0.015) with better scores for dry mouth (p=0.043), social eating (p=0.006), swallowing difficulties (p=0.001) and communication (p=0.049). CONCLUSION Supporting the barrier function alone does not help to reduce the severity and frequency of mucositis, nor the oral pain in high doses. Mucositis-induced pain may have a direct effect on malnutrition risk and quality of life in head and neck cancer patients. Powerful strategies are required to manage pain due to mucositis during curative radiotherapy.en_US
dc.fullTextLevelFull Texten_US
dc.identifier.doi10.5505/tjo.2019.2161en_US
dc.identifier.issn1300-7467
dc.identifier.scopus2-s2.0-85080964312en_US
dc.identifier.trdizinid383029en_US
dc.identifier.urihttps://hdl.handle.net/11411/2942
dc.identifier.urihttps://doi.org/10.5505/tjo.2019.2161
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/383029en_US
dc.identifier.wosWOS:000518098600006en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.issue1en_US
dc.language.isoenen_US
dc.nationalInternationalen_US
dc.numberofauthors4en_US
dc.pages40-46en_US
dc.publisherKare Publ.en_US
dc.relation.ispartofTürk Onkoloji Dergisi-Turkish Journal of Oncologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectHead and neck canceren_US
dc.subjectHyaluronic aciden_US
dc.subjectNutritionen_US
dc.subjectPolyvinyl prolidoneen_US
dc.subjectQuality of lifeen_US
dc.subjectRadiotherapyen_US
dc.titleMucositis-Induced Pain due to Barrier Dysfunction may have a Direct Effect on Nutritional Status and Quality of Life in Head and Neck Cancer Patients Receiving Radiotherapyen_US
dc.typeArticleen_US
dc.volume35en_US

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