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    Efficacy and Safety of Gamma Ventral Capsulotomy for Treatment-Resistant Obsessive-Compulsive Disorder: A Single-Center Experience
    (Elsevier Science Inc, 2020) Peker, Selcuk; Samanci, Mustafa Yavuz; Yilmaz, Meltem; Sengoz, Meric; Ulku, Nazan; Ogel, Kultegin
    BACKGROUND: Obsessive-compulsive disorder (OCD) is a chronic disease with a lifetime prevalence of 3% and is associated with severe impairment in familial and socio-occupational functioning. Gamma ventral capsulotomy (GVC) is a treatment choice in carefully chosen patients, with few published reports. In this study, we aimed to report the efficacy and safety of GVC in 21 patients with treatment-resistant OCD. METHODS: This is a retrospective single-center study. Twenty-one patients meeting the selection criteria were included. Patients were considered responders if there were >= 35% reduction in post-GVC Yale-Brown Obsessive Compulsive Scale scores and considered in remission if scores were <= 8. The mean and median clinical follow-up durations were 60.7 and 56 months, respectively (range, 38-149 months). RESULTS: The mean baseline Yale-Brown Obsessive Compulsive Scale score of 35.7 (n = 21) decreased to 15.3 (n = 20) at 36 months follow-up evaluation (P < 0.0001). Fifteen patients (75%) achieved a full response. Of those patients, 7 (35%) were considered to be in remission. There were no partial responders, and 5 patients (25%) were classified as nonresponders. The pre-GVC mean Beck Depression Inventory-II score of 35.1 (n = 21) decreased to 13.8 (n = 20) at 36 months follow-up evaluation (P < 0.0001). Three patients (14.3%) had a transient post-GVC headache that resolved within a week, and 2 patients (9.5%) had persistent headaches that responded to 2-week oral corticosteroid treatment. A brain cyst developed after GVC in 2 patients (10%). No clinically notable abnormalities were seen on neurologic examination at any follow-up. CONCLUSIONS: Gamma ventral capsulotomy is a reasonable treatment method in select patients with treatment-resistant OCD.
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    Screening Scale for Behavioral and Socioeconomic Risk Factors for Gambling Addiction: A Validity and Reliability Study
    (Turkish Green Crescent Soc, 2020) Tekin, Kinyas; Guliyev, Cavid; Yilmaz, Emre; Ogel, Kultegin; Yuksel, Begum Ceren
    This study aimed to develop a measurement tool suitable for determining the gambling risk levels in Turkey. A total of 128 outpatients at two facilities with complaints of gambling were included in the study. The South Oaks Gambling Screen (SOGS) was used in the study. The Gambling Risk Screening Scale (GRSS), which evaluated the level of gambling risk, was developed. The GRSS has two factors-gambling behavior and economic and social problems-and they account for 59% of the total variance. The factor loadings for the first factor ranged from 0.55 to 0.77, whereas for the second factor, the factor loading ranged from 0.77 to 0.95. The Cronbach's alpha of the entire scale was 0.84 and that of its subscales were 0.82 and 0.89. The cutoff point of the scale was 9.5, its sensitivity was 0.98, and its specificity was 0.87. The GRSS scores correlated statistically with the SOGS scores. These findings indicated that GRSS could be considered a valid and reliable scale for determining the gambling risk levels.
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    The pathway to care of patients with SUD who presented at addiction treatment centers (AMATEM) in Turkey
    (Routledge Journals, Taylor & Francis Ltd, 2022) Karakaya, Ibrahim; Sacakli, Gamze; Bilici, Rabia; Ogel, Kultegin
    Aim: Recent studies have shown that alcohol and drug use in Turkey is rising year on year. In order to prevent and treat substance use disorder (SUD), many Alcohol and Drug Research, Treatment and Training Centres (AMATEM) have been established in Turkey. The purpose of this study was to investigate the pathway to care of patients who presented at AMATEM. Method: A total 235 patients with SUD between16-69 age groups who presented at AMATEMs in 2017 were included in this study. A sociodemographic form and a structured self-report questionnaire consisting of 36 items assessing the pathways of care were given to all the patients. Data were analysed with descriptive statistics using SPSS software. Results: The majority of the patients included in the study were single (55%) and male (96%). Patients mostly had a secondary school level of education (51%) and social security (65%). The majority of the patients stated that they used more than one substance (44%), opiates (20%) or alcohol (18%). Conclusion: This is the first study evaluating the pathway of care in patients with SUD in Turkey. It was observed that a significant majority of patients with SUD presented to AMATEMs and patients who applied to different health institutions stated that they were mostly informed about SUD and AMATEM. There were also patients with negative attitudes towards AMATEMs and non-medical treatment seeking behavior other than AMATEM. Families, relatives and friends of patients with SUD have an important place in reaching the treatment.