The Impact of Attenuation Correction on Positron Emission Tomography/Computed Tomography and Positron Emission Tomography/Magnetic Resonance Image Quality: A Phantom Study

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dc.contributor.authorUlusoy, Yagmur Idil
dc.contributor.authorYeyin, Nami
dc.contributor.authorDemir, Mustafa
dc.date.accessioned2026-04-04T18:56:09Z
dc.date.available2026-04-04T18:56:09Z
dc.date.issued2025
dc.departmentİstanbul Bilgi Üniversitesi
dc.description.abstractObjective:The quality of positron emission tomography/computed tomography (PET/CT) and PET/magnetic resonance (MR) images is a critical factor affecting the diagnostic reliability of clinical studies. An image quality (IQ) phantom is used to evaluate PET IQ. This study aims to acquire PET IQ phantom images on PET/CT and PET/MR systems and investigate the effects of attenuation correction on IQ.Materials and Methods:The PET IQ phantom was filled with F-18 fluorodeoxyglucose to achieve a lesion/background ratio of 4/1. The phantom was imaged separately on two different PET/CT scanners and one PET/MR scanner. Region of interest (ROIs) was drawn on both raw and attenuation-corrected images. Contrast and contrast-to-noise ratios (CNRs) were calculated from ROI counts.Results:For the smallest lesion with a diameter of 10 mm without attenuation correction, the contrast values in PET/CT and PET/MR images were found to be 1.32, 1.68, and 1.76, respectively. In attenuation-corrected images of the same lesion, the contrast values were 1.55, 1.89, and 2.22, respectively. The CNR values for the attenuation-corrected 10 cm lesion were 13.92, 12.05, and 13.36, respectively.Conclusion:Attenuation correction significantly improved IQ, with attenuation-corrected images demonstrating higher contrast and CNR values.
dc.identifier.doi10.4103/jmp.jmp_31_25
dc.identifier.doi10.4103/jmp.jmp_31_25
dc.identifier.endpage571
dc.identifier.issn0971-6203
dc.identifier.issn1998-3913
dc.identifier.issue3
dc.identifier.pmid41163762
dc.identifier.scopus2-s2.0-105017676110
dc.identifier.scopusqualityQ4
dc.identifier.startpage565
dc.identifier.urihttps://doi.org/10.4103/jmp.jmp_31_25
dc.identifier.urihttps://hdl.handle.net/11411/10714
dc.identifier.volume50
dc.identifier.wosWOS:001584040700002
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherWolters Kluwer Medknow Publications
dc.relation.ispartofJournal of Medical Physics
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20260402
dc.snmzKA_Scopus_20260402
dc.subjectAttenuation Correction
dc.subjectContrast
dc.subjectContrast-To-Noise Ratio
dc.subjectPositron Emission Tomography/Computed Tomography Image Quality
dc.subjectPositron Emission Tomography/Magnetic Resonance Image Quality
dc.titleThe Impact of Attenuation Correction on Positron Emission Tomography/Computed Tomography and Positron Emission Tomography/Magnetic Resonance Image Quality: A Phantom Study
dc.typeArticle

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