Weight loss after intragastric botulinum toxin injection in different weight individuals

dc.contributor.authorKaraca, Fatih Can
dc.date.accessioned2024-07-18T20:07:02Z
dc.date.available2024-07-18T20:07:02Z
dc.date.issued2020
dc.departmentİstanbul Billgi Üniversitesien_US
dc.description.abstractBackground: Intragastric injection of Botulinum toxin A has been shown to induce weight loss, slowering gastric motility as a result of inhibition of the acetylcholine-mediated gastric contractions. The aim of this study was to observe the effects of endoscopic intragastric injections of intragastric injection of botulinum toxin A in obese patients. Material and Method: A total dose of 400 U intragastric injection of botulinum toxin A was injected endoscopically into the antrum, corpus and fundus regions of the stomach. The follow-up results of 102 patients sub-grouped according to body mass indices values and evaluated the weight loss status were evaluated. Weight loss data was collected on the monthly follow-up visits for three consecutive months. Results: At the end of the third month, all subjects lost body weight, with a mean total weight loss ratio ranging between 4.76-19.47%. Mean total body weight loss percentages were significantly higher in Class II and III obese subjects compared to the normal- and over-weight and Class I obese individuals. Gastrointestinal adverse effects were observed in only five (4.9%) of the patients. Conclusion: Intragastric injection of botulinum toxin A administration with a dose of 400 U is a convenient method for weight loss for the individuals of different body mass indices.en_US
dc.identifier.doi10.32322/jhsm.733872
dc.identifier.endpage300en_US
dc.identifier.issn2636-8579
dc.identifier.issue3en_US
dc.identifier.startpage295en_US
dc.identifier.trdizinid501072en_US
dc.identifier.urihttps://doi.org/10.32322/jhsm.733872
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/501072
dc.identifier.urihttps://hdl.handle.net/11411/5750
dc.identifier.volume3en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofJournal of health sciences and medicine (Online)en_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleWeight loss after intragastric botulinum toxin injection in different weight individuals
dc.typeArticle

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