Unal, SemraEkren, NazmiSengil, Ahmet Z.Oktar, Faik N.Irmak, SterOral, OzlemSahin, Yesim M.2024-07-182024-07-1820181552-49731552-4981https://doi.org/10.1002/jbm.b.34046https://hdl.handle.net/11411/6939Hydroxyapatite (HA), obtained from bovine bones, was successfully reinforced with hexagonal boron nitrite (h-BN). h-BN/HA composites, with BN content up to 1.5 wt %, were sintered at various temperatures between 1000 and 1300 degrees C, in air. Well-sintered samples were obtained after sintering at 1200 and 1300 degrees C. The presence of h-BN contributed to dense, fine, and well-crystallized microstructure. The results of X-ray diffraction analysis and FT-IR spectroscopy showed that the produced composites comprised biphasic beta-TCP/HCA (HCA: carbonate partially substituted HA). High values of mechanical properties were achieved, namely compression strength 155 MPa for the sample 0.5% h-BN/HA and Vickers microhardness of 716 HV for the samples 1.5% h-BN/HA, both sintered at 1300 degrees C. U2OS human bone osteosarcoma proliferation and cell viability showed no adverse effect in the presence of h-BN/HA, suggesting the potential use of the produced materials as safe biomaterials in bone tissue engineering. (C) 2017 Wiley Periodicals, Inc.eninfo:eu-repo/semantics/closedAccessCompositesHydroxyapatiteBovine BoneHexagonal Boron NitrideBioceramicMechanical-PropertiesSintering TemperatureApatiteNanoparticlesNanotubesBhaArticle2-s2.0-8503482746710.1002/jbm.b.340462392629168913Q22384106Q2WOS:000442988800030